Thermo Fisher Scientific PTH1R Polyclonal Antibody
PTH1R 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 인간 및 비인간 영장류 반응성. IHC(P)에서 2 µg/mL로 검증됨. 항원 친화 크로마토그래피로 정제되어 PBS에 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific PTH1R Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from internal region of human PTH1R |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551485 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Monkey (100%)
- Orangutan, Gibbon (95%)
- Bovine, Dog (89%)
- Marmoset (84%)
Target Information
Parathyroid hormone receptor 1 (PTH1R) is a member of the G-protein coupled receptor family.
This receptor binds parathyroid hormone (PTH) and parathyroid hormone-like hormone (PTHLH).
Its activity is mediated by G proteins that activate adenylyl cyclase and a phosphatidylinositol-calcium second messenger system.
Defects in this receptor are associated with Jansen’s metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), and enchondromatosis.
PTH1R expression has been reported in bone, breast, brain, colon, GI tract, kidney, liver, placenta, skin, umbilical cord, and uterus.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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