Thermo Fisher Scientific KLC1 Recombinant Rabbit Monoclonal Antibody (JE54-47)
KLC1 단백질을 인식하는 토끼 단클론 항체로, Western blot, IHC, ICC, FACS 등 다양한 응용에 적합합니다. HEK293 세포에서 발현된 recombinant 항체이며, Protein A로 정제되었습니다. 인체, 마우스, 랫트 시료에 반응하며 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE54-47 |
| Immunogen | Recombinant protein within Human KLC1 aa 461–573 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2890463 |
Target Information
Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, responsible for transporting various cargos along microtubules toward their plus ends. The heavy chains provide motor activity, while the light chains bind to cargos.
The KLC1 gene encodes a kinesin light chain that associates with kinesin heavy chain through its N-terminal domain. Six tetratricopeptide repeat (TPR) motifs are involved in cargo binding, including vesicles, mitochondria, and the Golgi complex.
Kinesin light chains act as adapter molecules rather than motors. Although previously named kinesin 2, this gene is not part of the kinesin-2 heavy chain subfamily. Alternative splicing produces isoforms with distinct C-termini that may bind different cargos.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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