Thermo Scientific™

2`-Fluoro-Bz-A Phosphoramidite, standard grade, 28-400 finish bottle

2-Fluoro-Bz-A CEP is a phosphoramidite containing 5 DMT and the nucleoside adenosine (A) with 2`-Fluoro protection, for use in oligonucleotide자세히 알아보기

2-Fluoro-Bz-A CEP is a phosphoramidite containing 5 DMT and the nucleoside adenosine (A) with 2-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2-OH), the 2-F modification has been proven useful in antisense, siRNA, and aptamer applications. The standard grade marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 28-400 finish neck style, which is compatible with most MerMade synthesizers.

Features:
• Full chemical name—5-O-(4,4-Dimethoxytrityl)-N6-benzoyl-2-fluoroadenosine-3-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C47H51FN7O7P
• Base—A
• Base Protection—Bz
• Formula weight—875.92 g/mol
• HPLC purity—>98%
• 31P NMR purity—≥98%

사양

용도(장비)MerMade Synthesizers

제품 유형2in-Fluoro-Bz-A CEP

뉴클레오시드 유형Adenosine (A)

시약 특징2in-Fluoro modified

배송 조건Room Temperature

순도98%

수량0.5 g

시약 유형Phosphoramidite

등급Standard

핵산 유형RNA

형태Powder

Unit SizeEach