Thermo Scientific™

TheraPure™ 2`-Fluoro-U Phosphoramidite, serum vial bottle

2-Fluoro-U CEP is a phosphoramidite containing 5 DMT and the nucleoside uridine (U) with 2`-Fluoro protection, for use in oligonucleotide자세히 알아보기

2-Fluoro-U CEP is a phosphoramidite containing 5 DMT and the nucleoside uridine (U) with 2-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2-OH), the 2-F modification has been proven useful in antisense, siRNA, and aptamer applications. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 20-mL amber bottle with a serum vial neck style, which is compatible with most Applied Biosystems synthesizers and AKTA synthesizers.

Features:
• Full chemical name—5-O-(4,4-Dimethoxytrityl)-2-fluorouridine-3-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C39H46FN4O8P
• Base—A
• Formula weight—748.8 g/mol
• CAS number—146954-75-8
• HPLC purity—>98%
• 31P NMR purity—≥98%

사양

용도(장비)AKTA Synthesizers, Applied Biosystems Synthesizers

제품 유형2in-Fluoro-U CEP

뉴클레오시드 유형Uridine (U)

시약 특징2in-Fluoro modified

배송 조건Room Temperature

순도98%

수량1 g

시약 유형Phosphoramidite

등급TheraPure™

핵산 유형RNA

제품라인TheraPure™

형태Powder

Unit SizeEach