Thermo Fisher Scientific Monoamine Oxidase B Polyclonal Antibody
Monoamine Oxidase B 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 신경전달물질 대사 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
| ELISA | 1:1,000–1:10,000 | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 163–501 of Human Monoamine Oxidase B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.51 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545814 |
Product Specific Information
- Recommended positive controls: HepG2, mouse liver
- Predicted reactivity: Mouse (87%), Rat (86%), Dog (94%), Pig (90%), Bovine (90%), Guinea pig (86%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MAOB (Monoamine Oxidase B), also known as MAO, BRAIN, or AMINE OXIDASE (FLAVIN-CONTAINING) B, is a protein encoded by the MAOB gene in humans.
It belongs to the flavin monoamine oxidase family and is mapped on Xp11.3. MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines, playing a critical role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues.
This enzyme preferentially degrades benzylamine and phenylethylamine, and also degrades dopamine.
MAO-B inhibition enhances dopaminergic activity and reduces hydrogen peroxide production, thereby decreasing reactive oxygen species formation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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