Thermo Fisher Scientific MMP3 Monoclonal Antibody (OTI4C12), TrueMAB
인간 MMP3 단백질(aa 246-477)을 항원으로 제작된 단클론 항체로 Western blot에 적합합니다. Mouse IgG1 아이소타입이며, 무보존제 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능하며, 조직 재생 및 단백질 분해 연구에 활용됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 246–477 of human MMP3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted as a pro-protein and activated by extracellular proteinase cleavage. MMP3 binds zinc and calcium ions and exhibits metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin, and plays a role in wound repair and tissue remodeling. Mutations in this gene have been associated with coronary heart disease 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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