Thermo Fisher Scientific TMEM100 Monoclonal Antibody (OTI10G3), TrueMAB
TMEM100 단백질을 인식하는 Mouse Monoclonal Antibody로, Western blot, IHC, ICC/IF에 사용 가능. 고순도 친화 크로마토그래피 정제. 동결건조 형태로 제공되며 재구성 용이. 인간 시료에 반응하며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10G3 |
| Immunogen | Full length human recombinant protein of human TMEM100 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TMEM100 plays a role in embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway activated by bone morphogenetic proteins (e.g., GDF2/BMP9 and BMP10).
It also regulates nociception by modulating the interaction between TRPA1 and TRPV1 in dorsal root ganglia (DRG) neurons, weakening their interaction and enhancing TRPA1 activity.
[Source: UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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