Thermo Fisher Scientific ASXL1 Polyclonal Antibody
ASXL1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 및 마우스 시료에 반응하며, IHC(P)에서 1:20–1:100 희석으로 사용 가능. 액상 형태로 PBS 및 글리세롤 버퍼에 보관되며, 연구용으로 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human ASXL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2688540 |
Product Specific Information
Predicted to react with Mouse samples.
Target Information
Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG).
Acts as coactivator of RARA and RXRA through association with NCOA1.
Acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters.
Acts as corepressor for PPARG and suppresses its adipocyte differentiation-inducing activity.
Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at Lys-119 (H2AK119ub1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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