Thermo Fisher Scientific STAT6 Polyclonal Antibody, FITC
STAT6 단백질을 표적하는 FITC 결합 폴리클로날 항체로, 인간·마우스·랫트 반응성. WB, IHC, ELISA, IP 등 다양한 응용 가능. IL-4 및 IL-13 매개 면역 반응 연구에 적합. 액상 형태로 -20°C 암소 보관.
- 카탈로그번호
- STAT6-Y-FITC
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific STAT6 Polyclonal Antibody, FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 655–705 of human STAT6 protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL-13. STAT6-deficient (Stat6-/-) models show impaired IL-4-mediated functions, including Th2 helper T-cell differentiation, surface marker expression, T-cell proliferation, immunoglobulin class switching to IgE, and reduced IL-4-mediated proliferation. STAT6 mRNA is expressed in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung, and placenta. STAT6 plays a critical role in Th2 immune response and IL-4-mediated biological processes, existing in two isoforms: STAT6a and STAT6c.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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