Thermo Fisher Scientific PSA Recombinant Rabbit Monoclonal Antibody (SD07-45)
Recombinant rabbit monoclonal antibody (clone SD07-45) targeting human PSA. Validated for WB, IHC (P), and ICC/IF. Produced in HEK293 cells, purified via Protein A, and supplied as a liquid at 1 mg/mL. Suitable for prostate cancer research.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SD07-45 |
| Immunogen | Recombinant protein within human prostate specific antigen (aa 198–261) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2911589 |
Product Specific Information
- Positive Control: PC-3M, human prostate tissue, human prostate carcinoma tissue
- Subcellular Location: Secreted
Target Information
Prostate Specific Antigen (PSA) is a chymotrypsin-like serine protease belonging to the kallikrein family, produced by the prostate epithelium and abundant in seminal fluid. PSA is detectable in the sera of patients with prostatic carcinoma and is primarily complexed with alpha-1-antichymotrypsin (ACT). A higher proportion of PSA-ACT complex is found in prostate cancer compared to benign prostatic hyperplasia. PSA serves as a marker for confirming prostatic acinar cell origin in primary and metastatic carcinoma and for distinguishing non-prostatic carcinoma mimics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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