Invitrogen™

Tetramethylrhodamine (TAMRA) Azide (Tetramethylrhodamine 5-Carboxamido-(6-Azidohexanyl)), 5-isomer

The red-fluorescent tetramethylrhodamine (TAMRA) azide can be reacted with terminal alkynes via a copper-catalyzed click reaction. Click chemistry describes a자세히 알아보기

The red-fluorescent tetramethylrhodamine (TAMRA) azide can be reacted with terminal alkynes via a copper-catalyzed click reaction. Click chemistry describes a class of chemical reactions that use bio-orthogonal or biologically unique moities to label and detect a molecule of interest using a two-step procedure. The two-step reaction procedure involves a copper-catalyzed triazole formation of an azide and an alkyne. Click reactions have several characteristics: the reaction between the detection moieties is efficient; no extreme temperatures or solvents are required; the reaction product is stable; the components of the reaction are bioinert; and perhaps most importantly, no side reactions occur – the label and detection tags react selectively and specifically with one another. Unlike traditional chemical reactions utilizing succinimidyl esters or maleimides that target amines and sulfhydryls – functional groups that are not unique – click chemistry-labeled molecules can be applied to complex biological samples and be detected with unprecedented sensitivity due to extremely low background.

사양

형식Solid

수량0.5 mg

제품 유형Tetramethylrhodamine Azide

분자량554.65 Da

용해도DMSO (Dimethylsulfoxide)

화학물질 반응성Alkyne

검출 방법Fluorescence

반응성 그룹Azide

배송 조건Room Temperature

반응성 부분Amine, Azide

라벨 또는 염료TAMRA™ Isomers, TMR (Tetramethylrhodamine)

라벨 유형Classic Dyes

색상Orange

제품라인Molecular Probes™

Unit Size0.5 mg