Thermo Fisher Scientific NAIF1 Polyclonal Antibody
Rabbit polyclonal antibody against human NAIF1, validated for WB and ELISA. Recognizes human, mouse, and rat samples. Supplied as liquid, affinity purified, 1.18 mg/mL concentration. Stored at -20°C in PBS with 50% glycerol.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–110 of human NAIF1 (NP_9310451) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.18 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806011 |
Product Specific Information
- Immunogen sequence: MAVPAKKRKM NFSEREVEII VEELELKKHL LVNHFNAGVP LAAKSAAWHG ILRRVNAVAT CRRELPEVKK KWSDLKTEVR RKVAQVRAAV EGGEAPGPTE EDGAGGPGTG
- Positive Samples: LO2, A375, 293T, OVCAR3, Mouse brain, Mouse liver, Rat brain, Rat liver
- Cellular Location: Nucleus
Target Information
Human NAIF1 is located on chromosome 9q34.11 and encodes a 327-amino-acid protein with a homeodomain-like region and two nuclear localization signals at its N-terminal region.
NAIF1 is conserved among human, mouse, crab-eating macaque, dog, chicken, and frog, and shares no obvious homology to known genes or proteins.
NAIF1 localizes predominantly in the nucleus. Overexpression of NAIF1 inhibits cell growth and induces apoptosis, decreasing mitochondrial membrane potential and activating caspase-3.
In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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