Thermo Fisher Scientific RASSF7 Polyclonal Antibody
RASSF7 단백질을 인식하는 Goat Polyclonal 항체로, Western Blot에 최적화됨. 인공 펩타이드 항원(aa 152-166) 기반으로 제작. 0.5 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관. 세포 스트레스 반응 및 세포분열 연구에 활용 가능.
- 카탈로그번호
- PA518894
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (CTDLRGLELRVQRN) corresponding to the internal amino acids of RASSF7 (aa 152–166) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10985334 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, the anti-apoptotic effect ceases due to degradation of the RASSF7 protein via the ubiquitin-proteasome pathway. Required for activation of AURKB and chromosomal congression during mitosis, where it stimulates microtubule polymerization. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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