Thermo Fisher Scientific DACH2 Polyclonal Antibody
DACH2 단백질을 인식하는 염소 다클론 항체로, Western blot에 적합합니다. 합성 펩타이드(aa 176-189)를 면역원으로 사용하였으며, 0.5 mg/mL 농도의 액상 형태입니다. 마우스 반응성이 확인되었고, 인간 단백질에도 반응이 예측됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.03–0.1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (TRKQAVNSSRPGR) corresponding to the internal amino acids of DACH2 (aa 176–189) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10977853 |
Product Specific Information
- This antibody is predicted to react with human based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
This gene is one of two genes that encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb, and genital disc of the fly.
The encoded protein contains two characteristic dachshund domains:
- N-terminal domain: responsible for DNA binding
- C-terminal domain: responsible for protein–protein interactions
This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in the regulation of organogenesis and myogenesis and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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