Thermo Fisher Scientific DACH2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.03–0.1 µg/mL

Product Specifications

Product Specific Information

• This antibody is predicted to react with human based on sequence homology.
• Tested in Peptide ELISA: antibody detection limit dilution 64,000.

Target Information

This gene is one of two genes that encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb, and genital disc of the fly.
The encoded protein contains two characteristic dachshund domains:

• N-terminal domain: responsible for DNA binding
• C-terminal domain: responsible for protein–protein interactions

This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in the regulation of organogenesis and myogenesis and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.