Thermo Fisher Scientific CKMT2 Polyclonal Antibody
Thermo Fisher Scientific의 CKMT2 Polyclonal Antibody는 인간 및 생쥐 시료에서 미토콘드리아 크레아틴 키나아제 검출에 적합합니다. Western blot과 IHC에 사용 가능하며, 항원 친화 크로마토그래피로 정제된 고품질 항체입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 75–415 of Human sMtCK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris Glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546817 |
Product Specific Information
- Recommended positive controls: 293T
- Predicted reactivity: Mouse (98%), Rat (98%), Dog (98%), Pig (99%), Rabbit (97%), Chicken (89%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Mitochondrial creatine kinase (MtCK) transfers high-energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family and exists as sarcomeric and ubiquitous isoenzymes encoded by separate genes. MtCK forms dimers and octamers, unlike cytosolic isoenzymes that form only dimers. Sarcomeric MtCK shares 80% homology with ubiquitous MtCK coding exons. The gene includes motifs common to nuclear genes encoding mitochondrial proteins, suggesting roles in coordinated gene activation during mitochondrial biogenesis. Three transcript variants encoding the same protein have been identified.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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