Thermo Fisher Scientific MMP14 Monoclonal Antibody (3A1)
Rabbit monoclonal antibody (clone 3A1) targeting human MMP14. Validated for WB, IHC, ICC/IF, and Flow Cytometry. Supplied unconjugated in liquid form at 1 mg/mL. For research use only; store at -20°C and ship on wet ice.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A1 |
| Immunogen | Recombinant human MMP14 between amino acids 150–250 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes including arthritis and metastasis. Most MMPs are secreted as inactive proproteins activated by extracellular proteinases. The protein encoded by this gene belongs to the membrane-type MMP (MT-MMP) subfamily, containing a transmembrane domain suggesting cell surface expression. This protein activates MMP2, contributing to tumor invasion mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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