Thermo Fisher Scientific CD179b Recombinant Rabbit Monoclonal Antibody (8H16L35)
CD179b 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot과 면역세포염색(ICC/IF)에 적합합니다. 높은 특이성과 민감도를 제공하며, 로트 간 일관성이 우수하고 동물 유래 성분이 없습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:10,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8H16L35 |
| Immunogen | Peptides corresponding to human CD179b (aa93–aa112, aa152–aa167) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2762380 |
Product Specific Information
This antibody is predicted to react with Monkey, Cat, Pig, and Rat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences are cloned from immunoreactive rabbits, and individual clones are screened for optimal performance.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to large rabbit immune repertoire
Target Information
CD179b (preB cell receptor component) is expressed on proB and preB cells, playing a key role in:
- Signal transduction for proliferation and differentiation
- Allelic exclusion at the Ig heavy chain locus
- Promotion of Ig light chain rearrangements
This gene encodes a surrogate light chain subunit and belongs to the immunoglobulin gene superfamily. Mutations may cause B cell deficiency and agammaglobulinemia, an autosomal recessive disorder characterized by low or absent gamma globulins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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