Thermo Fisher Scientific TACR1 Polyclonal Antibody
Tachykinin Receptor 1을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 2–4 µg/mL로 사용됩니다. 인간, 개, 소 등 다양한 종에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 신경계 및 염증 관련 연구에 적합합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 2nd extracellular domain of human Neurokinin 1 Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551332 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey, Marmoset, Bovine, Dog (100%), Rabbit (94%).
Target Information
Tachykinin Receptor 1 (TACR1), a member of the Tachykinin Receptor subfamily, mediates phosphatidylinositol metabolism by the tachykinin substance P (neurokinin 1). It is associated with the management of depression, anxiety, and stress, and plays roles in regulating behavioral responses, neuronal survival, and cardiovascular and respiratory functions. TACR1 is implicated in rheumatoid arthritis and osteoarthritis progression. Two variants are produced by alternative splicing. Expression is primarily in brain, blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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