Thermo Fisher Scientific TCEAL7 Polyclonal Antibody
인간 및 생쥐 반응성의 TCEAL7 폴리클로날 항체로, Western blot에 적합합니다. 합성 펩타이드 항원을 기반으로 제작되었으며, 액상 형태로 1 mg/mL 농도입니다. NF-kappa-B 신호 조절 및 Cyclin D1 발현 연구에 활용됩니다.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TCEAL7 (Accession Q9BRU2), corresponding to amino acid residues R23–L73 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853514 |
Product Specific Information
This antibody detects endogenous levels of total TCEAL7.
Target Information
TCEAL7 plays a role in the negative regulation of NF-kappa-B signaling by modulating transcriptional activity of NF-kappa-B on its target gene promoters. It associates with the cyclin D1 promoter containing the Myc E-box sequence and represses cyclin D1 expression. Additionally, it regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres) and telomerase-positive cell lines.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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