Thermo Fisher Scientific TCF19 Polyclonal Antibody
TCF19 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, WB, IHC, ICC/IF 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 고순도 친화 크로마토그래피로 정제되어 연구용으로 안정적입니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TCF19 (Accession Q9Y242), corresponding to amino acid residues P241–P291 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853516 |
Product Specific Information
Antibody detects endogenous levels of total TCF19.
Target Information
TCF-19 (transcription factor 19), also known as SC1 or SC1-1, is a 345 amino acid protein that contains one FHA domain, a proline-rich domain, and one PHD-type zinc finger. Localizing to the nucleus, TCF-19 is a growth-regulated protein believed to function as a trans-activating factor involved in the transcription of genes related to late stages of cell cycle progression (G1 to S transition or entry into G2 and mitosis). TCF-19 is preferentially expressed in the G1-S phase of the cell cycle. The gene encoding TCF-19 localizes to a critical region on chromosome 6 associated with psoriasis vulgaris, a skin disorder characterized by hyperproliferation of epidermal cells. This suggests that TCF-19, through regulation of late cell cycle-specific genes, may play a role in the development of this disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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