Thermo Fisher Scientific PAK4 Monoclonal Antibody (OTI1C7), TrueMAB
Human PAK4 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(P) 실험에 적합. 재조합 PAK4(aa 1–308)를 면역원으로 사용. 동결건조 형태로 제공되며, PBS/trehalose buffer에 저장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–308 of human PAK4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PAK4 is a serine/threonine p21-activating kinase involved in actin cytoskeleton reorganization and filopodia formation.
It belongs to the PAK4–6 group, which is not activated by Cdc42/Rac binding.
PAK4 plays essential roles in embryonic viability, neuronal development, and tumor cell growth through activation of cancer prosurvival pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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