
Thermo Fisher Scientific Insulin/IRDN (beta-Cell and Insulinoma Marker) Monoclonal Antibody (E2-E3, 2D11-H5 (INS04, INS05))
베타세포 및 인슐린종 표지용 단클론 항체로, 인슐린 단백질 검출에 사용됩니다. IHC(P) 및 IHC(PFA) 실험에 적합하며, 다양한 종에 반응합니다. 정제된 단백질 A/G 방식으로 제조되었으며, 4°C에서 보관합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Pig, Rabbit |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E2-E3, 2D11-H5 (INS04, INS05) |
| Immunogen | Purified pig insulin, conjugated to KLH (E2-E3 & 2D11-H5) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids.
Insulin is a 51-amino acid polypeptide produced from a precursor peptide, proinsulin, which is post-translationally cleaved into two chains (peptide A and peptide B) linked via disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, a major cause of morbidity and mortality. Insulin is also present in tumors of β-cell origin such as insulinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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