Thermo Fisher Scientific Insulin/IRDN (beta-Cell and Insulinoma Marker) Monoclonal Antibody (E2-E3 (INS04))
Insulin 및 insulinoma 연구용 단클론 항체로, IHC(P) 및 IHC(PFA)에 적합. Bovine, Human, Mouse, Pig, Rabbit 반응성. E2-E3(INS04) 클론, Protein A/G 정제, 보존제 무첨가 PBS 용액 형태. -20°C 보관, 동결/해동 반복 피해야 함.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Pig, Rabbit |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E2-E3 (INS04) |
| Immunogen | Purified pig insulin, conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids.
Insulin is a 51-amino acid polypeptide produced from the precursor proinsulin, which is cleaved into two chains (peptide A and peptide B) linked by disulfide bonds, along with one molecule of C-peptide.
Insulin deficiency results in diabetes mellitus, a major cause of morbidity and mortality. Insulin is also present in tumors of β-cell origin such as insulinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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