Thermo Fisher Scientific Lamin B1 Polyclonal Antibody
Lamin B1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF, Flow Cytometry 등에 사용 가능. 고순도 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공되어 안정적 보관 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 0.5–1 µg/mL |
| Immunohistochemistry (Frozen) (IHC-F) | 0.5–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
| Flow Cytometry (Flow) | 1–3 µg/1×10⁶ cells |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived human Lamin B1 recombinant protein (Position: Q266–C583) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746722 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Laminins are extracellular matrix glycoproteins and major non-collagenous components of basement membranes. They are involved in cell adhesion, differentiation, migration, signaling, neurite outgrowth, and metastasis. Laminins consist of three non-identical chains (alpha, beta, gamma) forming a cruciform structure. Mutations in the LMNB1 gene are associated with autosomal dominant adult-onset demyelinating leukodystrophy (ADLD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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