
Thermo Fisher Scientific NFATC2 Monoclonal Antibody (2A4)
NFATC2 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 NFATC2에 반응하며 보존제가 없는 액상 형태로 제공됩니다. -20°C에서 보관하며 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A4 |
| Immunogen | NFATC2 (NP_036472, 812–921 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
HYSPTNQQLR CGSHQEFQHI MYCENFAPGT TRPGPPPVSQ GQRLSPGSYP TVIQQQNATS QRAAKNGPPV SDQKEVLPAG VTIKQEQNLD QTYLDDELID TRLSWIQNIL
Target Information
The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1 (NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3). These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein, NFAT5, differs from isoforms 1–4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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