Thermo Fisher Scientific PKD2 Polyclonal Antibody
PKD2 단백질의 비인산화 형태를 인식하는 Rabbit Polyclonal 항체입니다. Western blot 및 IHC에 적합하며, 인간 PKD2 합성 펩타이드를 면역원으로 제작되었습니다. 단기 4°C, 장기 -20°C 보관을 권장합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human PKD2 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2163385 |
Product Specific Information
This antibody is directed against the unphosphorylated form of PKD2. Cross-reactivity with phosphorylated forms has not yet been determined.
Target Information
The PKD2 gene encodes a member of the polycystin protein family containing multiple transmembrane domains and cytoplasmic N- and C-termini. The protein is an integral membrane protein involved in cell-cell and cell-matrix interactions. It may function in renal tubular development, morphology, and function, and modulate intracellular calcium homeostasis and signal transduction pathways. PKD2 interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene are associated with autosomal dominant polycystic kidney disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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