Thermo Fisher Scientific PKD2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:2,000

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Immunohistochemistry (IHC)

1:300-1:2,000

-

Immunocytochemistry (ICC/IF)

-

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Product Specifications

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from mouse PKD2 conjugated to blue carrier protein was used as the antigen.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2163366

Product Specific Information

This antibody is directed against the unphosphorylated form of PKD2, and the cross-reactivity with phosphorylated forms has not yet been determined.

Reconstitute in 100 µL of sterile water. When reconstituting, glycerol (1:1) may be added for an additional stability.

Target Information

This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.