Thermo Fisher Scientific MMP13 Monoclonal Antibody (OTI2D11), TrueMAB
Human MMP13 단백질을 인식하는 Mouse 단일클론 항체로 Western blot 및 IHC(Paraffin)에 최적화됨. Lyophilized 형태로 제공되며, PBS buffer와 trehalose 포함. 재구성 및 conjugation 실험에 적합하며, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:4,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D11 |
| Immunogen | Human recombinant protein fragment (aa 104–471 of human MMP13, produced in HEK293T cells) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MMP13 (collagenase 3) is involved in the degradation of extracellular matrix proteins, including fibrillar collagens (types I, II, III), fibronectin, TNC, and ACAN.
It exhibits highest activity toward soluble type II collagen and can also degrade collagen types IV, XIV, and X.
MMP13 functions in wound healing, tissue remodeling, cartilage degradation, bone development, mineralization, and ossification.
It is essential for normal embryonic bone development. Mutations can cause disorders such as spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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