Thermo Fisher Scientific Phospho-TOP2A (Ser1106) Polyclonal Antibody
Phospho-TOP2A (Ser1106) 항체로, 인간 및 마우스 시료에서 인산화된 TOP2A 단백질 검출에 적합. Western blot과 IHC(파라핀) 적용 가능. 항원 친화 크로마토그래피로 정제된 Rabbit Polyclonal IgG. 1 mg/mL 농도의 액상 형태로, -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of serine 1106 (E-E-S(p)-D-N) derived from Human TOP2A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609496 |
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
Target Information
Topo II alpha plays important roles in DNA synthesis and transcription, as well as chromosomal segregation during mitosis. It is a sensitive and specific marker of late S-, G2-, and M-phases in transformed and developmentally regulated normal cells. Additionally, Topo II alpha is implicated in drug resistance of tumor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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