Thermo Fisher Scientific SMNDC1 Polyclonal Antibody
Thermo Fisher Scientific의 SMNDC1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 Western blot과 ELISA에 적합합니다. Rabbit IgG 기반의 비결합 항체로, Affinity Chromatography로 정제되었으며 핵 및 Cajal body 내 단백질 검출에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–238 of human SMNDC1 (NP_005862.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.49 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804183 |
Product Specific Information
Immunogen sequence:
MSEDLAKQLA SYKAQLQQVE AALSGNGENE DLLKLKKDLQ EVIELTKDLL STQPSETLAS SDSFASTQPT HSWKVGDKCM AVWSEDGQCY EAEIEEIDEE NGTAAITFAG YGNAEVTPLL NLKPVEEGRK AKEDSGNKPM SKKEMIAQQR EYKKKKALKK AQRIKELEQE REDQKVKWQQ FNNRAYSKNK KGQVKRSIFA SPESVTGKVG VGTCGIADKP MTQYQDTSKY NVRHLMPQ
Positive Samples:
HeLa, Jurkat, HT-1080, PC-12, SH-SY5Y, SKOV3, Mouse thymus, Rat thymus
Cellular Location:
Cajal body, Nucleus, Nucleus speckle
Target Information
This gene is a paralog of the SMN1 gene, which encodes the survival motor neuron protein. Mutations in SMN1 cause autosomal recessive proximal spinal muscular atrophy. The SMNDC1 gene encodes a nuclear protein that is a constituent of the spliceosome complex, showing differential expression with abundant levels in skeletal muscle, and may share similar cellular functions with SMN1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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