Thermo Fisher Scientific CHD9 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CHD9. Recombinant protein control fragment (Product #RP-98769). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CHD9,uniProtId:Q3L8U1-1,ncbiNodeId:9606,antigenRange:1999-2117,antigenLength:2897,antigenImageFileName:PA5-61963_CHD9_Q3L8U1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61963_CHD9_Q3L8U1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639761

Product Specific Information

Immunogen sequence: RNYSQSKMAH SRTSTPLLQQ YQVALSASPL TSLPRLLDAK GIILEEMKVK SENLKEEPQS SEEESMSSVE TRTLIKSEPV SPKNGVLPQA TGDQKSGGKC ETDRRMVAAR TEPLTPNPA

Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 82%.

Target Information

CHD9 (chromodomain-helicase-DNA-binding protein 9), also known as chromatin-related mesenchymal modulator (CReMM), PPAR-α-interacting complex protein, kismet homolog 2 or CHROM1, is a 2,897 amino acid protein belonging to the Snf2/Rad54 helicase family. The CHD family of proteins are ATP-dependent chromatin remodeling enzymes which combine chromodomains with SWI2/Snf2 ATPase/helicase motifs and DNA-binding capability. Localized to the cytoplasm and the nucleus, CHD9 contains two chromodomains, one ATPbinding helicase domain and one C-terminal helicase domain. Chromodomains are protein regions of about 40-50 amino acid residues found in proteins associated with chromatin remodeling and manipulation. The domain is highly conserved among both plants and animals and is found in a large variety of proteins from many genomes. CHD9 acts as a transcriptional coactivator for PPARα and may also be an ATP-dependent chromatin remodeling protein. CHD9 is widely expressed at low levels and is present as three isoforms produced by alternative splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.