Thermo Fisher Scientific CHD9 Polyclonal Antibody
Human CHD9 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CHD9. Recombinant protein control fragment: Product #RP-98769 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639761 |
Product Specific Information
Immunogen sequence:
RNYSQSKMAH SRTSTPLLQQ YQVALSASPL TSLPRLLDAK GIILEEMKVK SENLKEEPQS SEEESMSSVE TRTLIKSEPV SPKNGVLPQA TGDQKSGGKC ETDRRMVAAR TEPLTPNPA
- Highest antigen sequence identity to orthologs:
- Mouse: 88%
- Rat: 82%
Target Information
CHD9 (chromodomain-helicase-DNA-binding protein 9), also known as chromatin-related mesenchymal modulator (CReMM), PPAR-α-interacting complex protein, kismet homolog 2, or CHROM1, is a 2,897 amino acid protein belonging to the Snf2/Rad54 helicase family.
CHD proteins are ATP-dependent chromatin remodeling enzymes combining chromodomains with SWI2/Snf2 ATPase/helicase motifs and DNA-binding capability.
Localized to both cytoplasm and nucleus, CHD9 contains two chromodomains, one ATP-binding helicase domain, and one C-terminal helicase domain.
Chromodomains (~40–50 amino acids) are conserved regions found in chromatin-associated proteins across plants and animals.
CHD9 acts as a transcriptional coactivator for PPARα and may function as an ATP-dependent chromatin remodeling protein.
It is widely expressed at low levels and exists in three isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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