Thermo Fisher Scientific Human LMX1B Synthetic Peptide
인간 LMX1B 단백질의 C-말단 17개 아미노산 서열을 기반으로 한 합성 펩타이드. 항체 PA5-34471의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 제공되며 PBS 버퍼에 0.1% BSA와 0.02% sodium azide 포함. 연구용 전용 시약.
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Thermo Fisher Scientific Human LMX1B Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the carboxy terminus of human LMX1B.
PEP-1513 can be used as a blocking peptide with polyclonal antibody PA5-34471.
Target Information
LMX1B (LIM homeobox transcription factor 1B) belongs to the LIM-homeodomain family, which plays a key role in developmental pattern formation.
LMX1B regulates mid-hindbrain patterning, and knockout (LMX1B-) mouse embryos show a severe reduction in midbrain dopaminergic neurons compared to wild-type.
LMX1B is important for both development and survival of dopamine neurons, while the related LMX1A is crucial for their differentiation.
LMX1A and LMX1B function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic neuronal progenitors.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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