Thermo Fisher Scientific Human LMX1A Synthetic Peptide
인간 LMX1A 단백질의 C-말단 16개 아미노산 서열 기반 합성 펩타이드입니다. 항체 PA5-34470의 블로킹 펩타이드로 사용 가능하며, 정제된 액상 형태로 제공됩니다. PBS 버퍼 내 보관하며 연구용으로 적합합니다.
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Thermo Fisher Scientific Human LMX1A Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human LMX1A.
PEP-1512 can be used as a blocking peptide with polyclonal antibody PA5-34470.
Target Information
The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are important for pattern formation during development.
LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter.
In the developing embryo, LMX1A is expressed along the neuraxis and contributes to the development of the roof plate of the vertebrae.
LMX1A is crucial for the differentiation of dopamine neurons, while the related LMX1B is important for both development and survival of these cells.
LMX1A may serve as a biomarker or risk factor in tumor aggressiveness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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