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Thermo Fisher Scientific DENND1C Polyclonal Antibody
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Human DENND1C 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200~1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보존. 클라트린 매개 내포 및 RAB35 활성화 연구에 적합.
- 판매단위
- pk
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마지막 업데이트 2025. 07. 27. 오전 10:55
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Thermo Fisher Scientific PA560105 DENND1C Polyclonal Antibody 100 ul pk판매 단위 pk
재고 1개
796,700원VAT 포함 876,370원
Thermo Fisher Scientific · Thermo Fisher Scientific DENND1C Polyclonal Antibody
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DENND1C. Recombinant protein control fragment (Product # RP-99238) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640513 |
Product Specific Information
- Immunogen sequence:
PSPPESPQIL APTKPNFDIA WTSQPLDPSS DPSSLEDPRA RPPKALLAER AHLQPREEPG ALNSPATPTS NCQKSQPSSR PRVADLKKCF E - Highest antigen sequence identity to orthologs:
- Mouse: 47%
- Rat: 45%
Target Information
Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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