Thermo Fisher Scientific PARP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,500

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50

-

Immunocytochemistry (ICC/IF)

2-3 µg/mL

View 1 publication 1 publication

Product Specifications

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from the C-terminal region of bovine PARP if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PARP1,uniProtId:P18493-1,ncbiNodeId:9913,antigenRange:1016,antigenLength:1016,antigenImageFileName:PA5-16561_PARP1_P18493-1_Rabbit.svg,antigenImageFileNamePDP:PA5-16561_PARP1_P18493-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10985586

Product Specific Information

PA5-16561 was successfully used to detect PARP in WB, IHC and IF applications.

PA5-16561 targets PARP (Poly ADP-Ribose Polymerase) in WB applications and shows reactivity with mouse, Rat, Bovine, and Human samples.

The PA5-16561 immunogen is a synthetic peptide from the C-terminal region of bovine PARP.

Target Information

Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.