Thermo Fisher Scientific Beclin 2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human BECN2(Accession A8MW95), corresponding to amino acid residues V47-Q97. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Beclin 2,uniProtId:A8MW95-1,ncbiNodeId:9606,antigenRange:47-97,antigenLength:431,antigenImageFileName:PA5-100927_Beclin_2_A8MW95-1_Rabbit.svg,antigenImageFileNamePDP:PA5-100927_Beclin_2_A8MW95-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2850420

Product Specific Information

Antibody detects endogenous levels of total BECN1L1.

Target Information

Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.