Thermo Fisher Scientific TAS2R41 Polyclonal Antibody
TAS2R41 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간·마우스·랫트 시료에 반응합니다. Western blot과 IHC에 적합하며, 액상 형태로 1 mg/mL 농도입니다. 쓴맛 인지 관련 수용체 연구용으로 사용됩니다.
- 카탈로그번호
- PA599927
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TAS2R12, corresponding to a region within C-terminal amino acids |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2818860 |
Product Specific Information
Antibody detects endogenous levels of total TAS2R12.
Target Information
TAS2R41 is a receptor that may play a role in the perception of bitterness and belongs to the G-protein receptor superfamily.
It is expressed mainly in taste receptor cells of the tongue and palate epithelia. Structurally, the TAS2R41 gene encodes a seven transmembrane receptor protein and is clustered with eight other taste receptor genes on chromosome 7.
Chloramphenicol acts as an agonist for TAS2R41. The receptor may be involved in sensing the chemical composition of gastrointestinal content and mediates PLC-beta-2 activation leading to TRPM5 gating.
TAS2R41 is expressed in subsets of taste receptor cells of the tongue, exclusively in gustducin-positive cells, and may help discriminate among bitter stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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