Thermo Fisher Scientific CD79a (B-Cell Marker) Monoclonal Antibody (HM57)
CD79a 단백질을 인식하는 HM57 클론 단일클론 항체로, 인간 및 다양한 종에 반응합니다. Western blot, IHC, ICC, Flow Cytometry 등 다양한 응용에 적합합니다. 단백질 A/G로 정제된 액상 항체이며, 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 0.25–0.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Non-human primate, Pig, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HM57 |
| Immunogen | Synthetic peptide corresponding to aa 202–216 (GTYQDVGSLNIADVQ) of human CD79a protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD79a is a disulphide-linked heterodimer that includes B29 (CD79b) polypeptide. It acts as a B lymphocyte antigen receptor with an antigen-specific surface component (Ig) that associates with Ig-alpha and Ig-beta, essential for B-cell receptor expression and function.
CD79a appears at the pre-B cell stage and persists until the plasma cell stage, where it is found intracellularly. It is expressed in most precursor B-cell acute leukemias, B-cell lines, B-cell lymphomas, and some myelomas, but not in myeloid or T-cell lines.
Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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