
Thermo Fisher Scientific GSPT1 Polyclonal Antibody
GSPT1 단백질을 인식하는 Rabbit polyclonal antibody로, Western blot 및 IHC(P) 실험에 사용 가능. 인간 및 생쥐 시료에 반응하며, 고순도 affinity chromatography로 정제됨. PBS/glycerol buffer에 보관되며 연구용으로만 사용.
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- PA599621
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GSPT1 (Accession P15170), corresponding to amino acid residues N268–L318 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818554 |
Product Specific Information
Antibody detects endogenous levels of total eRF3/GSPT1.
Target Information
eRF3a (eukaryotic peptide chain release factor subunit 3a), also known as GSPT1 (G1 to S phase transition 1), is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination.
Human eRF3a shares 94% sequence identity with its mouse counterpart, suggesting a conserved function between species.
The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome.
The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-99621_GSPT1_P15170-1_Rabbit.svg, PA5-99621_GSPT1_P15170-1_Rabbit_PDP.jpeg)
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