Thermo Fisher Scientific Pellino 2 Polyclonal Antibody
Human Pellino 2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 최적화되어 있음. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 0.87 mg/mL 농도. HeLa, HepG2, HCT116 세포에 적합하며 다양한 종에 예측 반응성 있음.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 166–420 of Human Pellino 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.87 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548175 |
Product Specific Information
- Recommended positive controls: HeLa, HepG2, HCT116
- Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (80%), Xenopus laevis (80%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 Lys-63-linked polyubiquitination and possibly Lys-48-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. [UniProt]
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-30701_Pellino_2_Q9HAT8-1_Rabbit.svg, PA5-30701_Pellino_2_Q9HAT8-1_Rabbit_PDP.jpeg)
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