Thermo Fisher Scientific LIS1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PAFAH1B1. Recombinant protein control fragment (Product #RP-100462). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LIS1,uniProtId:P43034-1,ncbiNodeId:9606,antigenRange:16-161,antigenLength:410,antigenImageFileName:PA5-82710_LIS1_P43034-1_Rabbit.svg,antigenImageFileNamePDP:PA5-82710_LIS1_P43034-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2789866

Product Specific Information

Immunogen sequence: ADYLRSNGYE EAYSVFKKEA ELDVNEELDK KYAGLLEKKW TSVIRLQKKV MELESKLNEA KEEFTSGGPL GQKRDPKEWI PRPPEKYALS GHRSPVTRVI FHPVFSVMVS ASEDATIKVW DYETGDFERT LKGHTDSVQD ISFDHS

Target Information

VAMP7 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family, localizing to late endosomes and lysosomes. VAMP7 is thought to mediate the fusion of endosomes to their target lysosomes as well as other exocytosis events during phagocytosis and neuritogenesis. VAMP7 interacts with the VPS9 ankyrin repeat protein VARP, a protein that localizes to early endosomes and thought to regulate endosome dynamics. Together with CD82, VAMP7 can modulate the signaling of EGFR by regulating its endocytosis from the plasma membrane.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.