Thermo Fisher Scientific AGR2 Monoclonal Antibody (10E2)

Applications

Tested Dilution

Publications

Western Blot (WB)

4-6 µg/mL

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Immunohistochemistry (IHC)

-

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Immunohistochemistry (Paraffin) (IHC (P))

5 µg/mL

-

Immunohistochemistry (Frozen) (IHC (F))

-

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Immunocytochemistry (ICC/IF)

-

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Product Specifications

Species Reactivity

Bovine, Dog, Horse, Human, Mouse, Non-human primate, Rat

Published species

Dog

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

10E2

Immunogen

A portion of amino acids 50-100 of human AGR2 was used as the immunogen for the antibody. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AGR2,uniProtId:O95994-1,ncbiNodeId:9606,antigenRange:50-100,antigenLength:175,antigenImageFileName:MA5-16244_AGR2_O95994-1_House_mouse.svg,antigenImageFileNamePDP:MA5-16244_AGR2_O95994-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2537762

Target Information

AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.