Thermo Fisher Scientific AGR2 Monoclonal Antibody (10E2)
AGR2 단백질을 표적으로 하는 마우스 단클론 항체로 다양한 종에서 반응. Western blot, IHC 등 다양한 응용 가능. 0.5 mg/mL 농도의 액상 형태이며 Protein G 정제. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 4–6 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL | – |
| Immunohistochemistry (Frozen) (IHC (F)) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Dog, Horse, Human, Mouse, Non-human primate, Rat |
| Published Species | Dog |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10E2 |
| Immunogen | A portion of amino acids 50–100 of human AGR2 was used as the immunogen for the antibody. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2537762 |
Target Information
AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins involved in metastasis induction and p53 tumor suppressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumors. AGR2 is ubiquitously expressed and upregulated in prostate, breast, lung, renal, and endometrial carcinomas. AGR2 expression is positively correlated with estrogen receptor (ER) and negatively correlated with epidermal growth factor receptor (EGFR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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