Thermo Fisher Scientific SEPT5 Polyclonal Antibody
Human SEPT5 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(Paraffin)에서 1:20~1:50 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤로 안정화. 세포분열 관련 SEPT5 연구에 적합한 연구용 항체.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SEPT5. Recombinant protein control fragment (Product #RP-103688) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791772 |
Product Specific Information
Immunogen sequence:
VPLIAKADCL VPSEIRKLKE RIREEIDKFG IHVYQFPE
Target Information
This gene belongs to the septin family of nucleotide-binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are conserved across species and regulate cytoskeletal organization.
Disruption of septin function leads to cytokinesis defects, resulting in multinucleate or polyploid cells.
The SEPT5 gene is mapped to 22q11, a region often deleted in DiGeorge and velocardiofacial syndromes.
A translocation involving the MLL gene and SEPT5 has been observed in acute myeloid leukemia.
Two transcripts (2.2 kb and 3.5 kb) have been identified, with alternative polyadenylation sites and splicing variants.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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