Thermo Fisher Scientific Mouse IL-17E (IL-25) Recombinant Protein, PeproTech
마우스 유래 IL-17E(IL-25) 재조합 단백질로, E. coli에서 발현된 35 kDa 동종이합체 형태의 사이토카인입니다. ≥98% 순도 보장, 엔도톡신 <1 EU/µg. HT-29 세포에서 GROα 유도 활성 검증됨. 연구용으로 염증 반응 및 면역 조절 연구에 적합.
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Applications
Functional Assay (Functional)
- Assay-dependent
In vitro Assay (IV)
- Refer to related publications (2)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Mouse |
| Published Species | Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | MLRIQEGCSH LPSCCPSKEQ EPPEEWLKWS SASVSPPEPL SHTHHAESCR ASKDGPLNSR AISPWSYELD RDLNRVPQDL YHARCLCPHC VSLQTGSHMD PLGNSVPLYH NQTVFYRRPC HGEEGTHRRY CLERRLYRVS LACVCVRPRV MA |
| Molecular Weight | 35 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% (SDS-PAGE, HPLC) |
| Endotoxin Concentration | <1 EU/µg |
| Activity | Induces GROα (CXCL1) secretion in HT-29 human colon adenocarcinoma cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Murine IL-17E is a 35.0 kDa disulfide-linked homodimer consisting of two 152-amino-acid polypeptide chains.
This product is shipped at ambient temperature. For storage, handling, and reconstitution details, refer to the lot-specific Certificate of Analysis.
Target Information
Interleukin 25 (IL-25) is a member of the IL-17 family, identified as a proinflammatory cytokine produced by Th17 effector cells. It contributes to autoimmune processes such as Rheumatoid Arthritis by activating NF-κB and stimulating IL-8 production. IL-25 activity is regulated by IL-23, IL-5, and TGF-β.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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