Thermo Fisher Scientific MTLR Polyclonal Antibody
Thermo Fisher Scientific의 MTLR Polyclonal Antibody는 인간 MTLR 단백질을 인식하는 Rabbit IgG 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. 고순도 Protein A 정제 제품으로 안정적인 결과를 제공합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human MTLR, amino acids 251–350 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Motilin is a conserved 22 amino acid peptide hormone secreted from enterochromaffin cells of the gastrointestinal tract. Within the intestines, motilin potentiates intestinal motility by inducing contractions of the duodenum and through binding to surface receptors designated as GPR38 (G-protein coupled receptor 38). These receptors are predominantly expressed in the stomach, thyroid, and bone marrow, and are related to other G-protein coupled receptors in the pituitary and hypothalamus that mediate signaling for growth hormone secretagogues. The gene encoding GPR38 is alternately spliced at the carboxy terminus to generate two related proteins, GPR38-A and GPR38-B. GPR38-A contains seven transmembrane domains, while GPR38-B is predicted to contain five. Consistent with other G-protein coupled receptors, GPR38 activates phospholipase C signal transduction pathways and induces intracellular calcium mobilization after binding of motilin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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