Thermo Fisher Scientific PTPN7 Monoclonal Antibody (AFPK32)
PTPN7 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 ELISA에 적합합니다. 마우스 IgG1 형식의 비표지 항체이며, 세포 신호전달 연구 및 T세포 수용체 경로 분석에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AFPK32 |
| Immunogen | Recombinant human protein purified from E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2538695 |
Product Specific Information
A suggested positive control for this product is Bosc23 cells transfected with Myc/His/HePTP.
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This gene is preferentially expressed in a variety of hematopoietic cells and acts as an early response gene in lymphokine-stimulated cells. The noncatalytic N-terminus of this PTP interacts with MAP kinases and suppresses MAP kinase activity.
PTPN7 is involved in regulating T cell antigen receptor signaling by dephosphorylating molecules related to the MAP kinase pathway. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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