Thermo Fisher Scientific Adenylate Cyclase 6 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500

Product Specifications

Product Specific Information

By Western blot, this antibody has only been tested on fusion protein.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions, and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.