Thermo Fisher Scientific HIP1R Polyclonal Antibody
HIP1R 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Affinity chromatography 정제, 액상 형태로 -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific HIP1R Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 300–600 of human HIP1R (NP_003950.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.35 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901173 |
Product Specific Information
Positive Samples: U-87MG, 293T, HeLa, Mouse brain, Mouse spleen, Mouse liver, Rat brain
Immunogen sequence:
KPVVVIPEEA PEDEEPENLI EISTGPPAGE PVVVADLFDQ TFGPPNGSVK DDRDLQIESL KREVEMLRSE LEKIKLEAQR YIAQLKSQVN ALEGELEEQR KQKQKALVDN EQLRHELAQL RAAQLEGERS QGLREEAERK ASATEARYNK LKEKHSELVH VHAELLRKNA DTAKQLTVTQ QSQEEVARVK EQLAFQVEQV KRESELKLEE KSDQLEKLKR ELEAKAGELA RAQEALSHTE QSKSELSSRL DTLSAEKDAL SGAVRQREAD LLAAQSLVRE TEAALSREQQ RSSQEQGELQ G
Target Information
Huntingtin disease, a neurodegenerative disorder, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a proapoptotic, cargo-specific adaptor protein potentially involved in the pathogenesis of Huntingtin disease. HIP-1 also plays a role in clathrin coat recruitment to lipid membranes and may contribute to tumorigenesis by supporting survival of precancerous and cancerous cells. Its expression is significantly associated with prostate and colon cancer metastasis, making HIP-1 a putative prognostic factor for these cancers.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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