Thermo Fisher Scientific BMPR1A Polyclonal Antibody
BMPR1A 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF, IP 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체이며, -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 6 publications |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 2 publications |
| Immunoprecipitation (IP) | Assay-dependent | View 1 publication |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from an internal region of the human BMPR-1A (bone morphogenetic protein receptor type 1A, Serine/threonine protein kinase receptor R5 (SKR5), activin receptor-like kinase-3 (ALK-3)), which differs from mouse and rat BMPR-1A by one nonconservative amino acid replacement. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533377 |
Target Information
BMPR1A is a Type I member of the TGF-beta receptor superfamily of transmembrane serine/threonine kinases that phosphorylates intracellular SMADs in response to bone morphogenic proteins. These receptors are closely related to the activin receptors, ACVR1 and ACVR2. Ligands of these receptors belong to the TGF-beta superfamily. TGF-betas and activins transduce signals through heteromeric complexes of type I and type II serine/threonine kinase receptors. Type II receptors bind ligands independently but require type I receptors for signaling, while type I receptors need type II receptors for ligand binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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