Thermo Fisher Scientific SPT6 Polyclonal Antibody
SPT6 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ICC/IF, ELISA, IP 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 액상 형태, 고순도 친화 크로마토그래피 정제. 연구용으로만 사용.
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- PA5120450
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Thermo Fisher Scientific SPT6 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 400–600 µg extracts |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1500–1726 of human SUPT6H (NP_003161.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.74 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914022 |
Product Specific Information
Positive test controls include U-87MG, Jurkat, HeLa, Mouse brain, Mouse heart, Mouse liver.
The target is usually found in the nucleus.
Immunogen sequence:
IFPTVNGLFR WFKDHYQDPV PGITPSSSSR TRTPASINAT PANINLADLT RAVNALPQNM TSQMFSAIAA VTGQGQNPNA TPAQWASSQY GYGGSGGGSS AYHVFPTPAQ QPVATPLMTP SYSYTTPSQP ITTPQYHQLQ ASTTPQSAQA QPQPSSSSRQ RQQQPKSNSH AAIDWGKMAE QWLQEKEAER RKQKQRLTPR PSPSPMIEST PMSIAGDATP LLDEMDR
Target Information
Transcription elongation factor that binds histone H3 and regulates transcription elongation and mRNA processing. Enhances elongation by RNA polymerase II and is required for activation by HIV-1 Tat. Forms complexes with IWS1 and RNAPII CTD to recruit mRNA export factors and histone-modifying enzymes, ensuring proper splicing and elongation-coupled H3K36 methylation. Also involved in class-switch recombination, somatic hypermutation, and activation of myogenic gene programs via epigenetic regulation.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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